When it comes to choosing the perfect pet, leopard geckos have undoubtedly gained immense popularity over the years. Their unique appearance, gentle temperament, and ease of care make them an ideal choice for both beginner and experienced reptile enthusiasts. However, as with any pet, potential owners should be aware of the potential health risks associated with keeping these fascinating creatures. 

Yes, leopard geckos can carry diseases, but the risk of transmission to humans or other pets is generally low. Proper care, hygiene, and routine veterinary check-ups can minimize potential health risks associated with these reptiles.

One common concern is whether leopard geckos carry diseases that could pose a threat to the health of their human caretakers or other pets in the household. In this blog post, we will explore the topic of diseases in leopard geckos, shedding light on the possible risks and precautions that should be taken to ensure a safe and enjoyable experience for both you and your pet.

Common Diseases in Leopard Geckos


Leopard geckos, like any other pets, can be susceptible to certain diseases and health issues. Here are some common diseases that may affect leopard geckos:

Metabolic Bone Disease (MBD): 

This condition occurs due to an imbalance of calcium and phosphorus, often caused by insufficient calcium intake, poor diet, or inadequate UVB lighting. Symptoms include soft or deformed bones, tremors, and difficulty moving.


Caused by a protozoan parasite, Cryptosporidium, this disease affects the gastrointestinal tract, leading to diarrhea, weight loss, and poor appetite. It can be challenging to treat and may require long-term medication.

Parasitic infections

Leopard geckos can be affected by various internal and external parasites, such as mites, pinworms, and coccidia. Symptoms include weight loss, lethargy, and poor appetite. Treatment usually involves anti-parasitic medications prescribed by a veterinarian.

Respiratory infections

Caused by bacteria or fungi, respiratory infections can occur due to poor husbandries, such as low temperatures or high humidity. Symptoms include wheezing, labored breathing, and nasal discharge. Antibiotics or antifungal medications may be needed for treatment.


This occurs when a leopard gecko ingests indigestible materials, such as substrate, which causes a blockage in its digestive system. Symptoms include constipation, bloating, and loss of appetite. Treatment may involve laxatives, warm baths, or, in severe cases, surgery.

Shedding issues (dysecdysis)

Improper shedding can lead to retained skin, which can constrict blood flow and cause complications, such as infections, loss of digits, or tail tips. Humidity adjustments and gentle manual removal of retained skin can help resolve shedding issues.

To minimize the risk of these diseases, maintain proper husbandry, provide a balanced diet, and ensure regular veterinary check-ups for your leopard gecko.

How to prevent disease in Leopard Geckos


Preventing disease in leopard geckos is crucial to ensure their overall health and well-being. By following these guidelines, you can reduce the risk of disease and maintain a thriving environment for your pet:

Proper enclosure setup

Provide an adequately sized terrarium with appropriate temperature gradients, humidity levels, and UVB lighting. Use a thermostat to regulate temperatures and a hygrometer to monitor humidity.

Appropriate substrate

Use a safe, non-particulate substrate, such as reptile carpet or slate tiles, to minimize the risk of impaction. Avoid using loose substrates like sand, which can be ingested and cause blockages.

Balanced diet

Offer a balanced diet comprising gut-loaded insects, such as crickets, mealworms, or dubia roaches, and supplement their diet with calcium and vitamin D3 to prevent metabolic bone disease.

Quarantine new pets

When introducing new reptiles to your collection, quarantine them for at least 4-6 weeks to monitor for any signs of illness before housing them with existing pets.

Regular veterinary care

Schedule routine check-ups with a qualified reptile veterinarian to monitor your leopard gecko’s health, detect potential issues early, and address any medical concerns promptly.

Maintain cleanliness

Clean the enclosure regularly, remove waste, and disinfect the habitat periodically to prevent the growth of harmful bacteria, fungi, or parasites. Wash your hands before and after handling your gecko to minimize the risk of disease transmission.

Monitor shedding

Ensure proper humidity levels during shedding periods and provide a moist hide to help facilitate the shedding process. Inspect your gecko after each shed to ensure no retained skin is present.

Manage stress

Minimize handling, especially during the initial weeks after bringing your gecko home or during periods of illness. Provide hiding spots within the enclosure to offer a sense of security and reduce stress.

By following these preventive measures, you can create a healthy environment for your leopard gecko and significantly reduce the risk of disease. Remember that early detection and prompt treatment are essential for addressing any health concerns that may arise.

Symptoms of illness in Leopard Geckos


Recognizing the symptoms of illness in leopard geckos is essential for ensuring timely medical intervention and proper care. Here are some signs that may indicate your leopard gecko is unwell:


Decreased activity levels or reluctance to move can be a sign of illness or discomfort.

Loss of appetite

A reduced appetite or refusal to eat over an extended period may indicate a health problem.

Weight loss

Rapid or unexplained weight loss can be a sign of an underlying issue, such as parasites or other infections.

Changes in feces

Diarrhea, constipation, or abnormal feces color or consistency may signal gastrointestinal problems.


Sunken eyes, wrinkled skin, or a lack of skin elasticity can indicate dehydration, which requires immediate attention.

Breathing difficulties

Wheezing, open-mouth breathing, or excessive mucus production may suggest a respiratory infection.

Swelling or lumps

Any unusual swelling, lumps, or bumps on your gecko’s body should be examined by a veterinarian.


Discharge from the eyes, nose, or mouth can be a sign of infection or irritation.

Shedding problems

Incomplete or irregular shedding, or retained skin, can lead to complications and may require intervention.

Limb deformities or weakness

Soft or bent bones, tremors, or difficulty moving can be symptoms of metabolic bone disease or other health concerns.

Changes in behavior

Aggression, hiding more than usual, or other behavioral changes can indicate stress or illness.

If you observe any of these symptoms in your leopard gecko, consult a qualified reptile veterinarian as soon as possible. Early detection and intervention are crucial for effectively treating health issues and ensuring the well-being of your pet.

Treatment options for Leopard Gecko diseases


Treatment options for leopard gecko diseases can vary based on the specific condition, its severity, and the overall health of the animal. It is essential to consult with a qualified reptile veterinarian to determine the appropriate course of action for your pet. Here are some general treatment options for common leopard gecko diseases:

Metabolic Bone Disease (MBD)

Treatment includes calcium and vitamin D3 supplementation, dietary adjustments, and proper UVB lighting to correct the underlying imbalance. In severe cases, a veterinarian may administer injectable calcium or prescribe additional medications.


This protozoan infection can be challenging to treat, but a veterinarian may prescribe medications, such as paromomycin, to help manage the symptoms. Supportive care, including fluid therapy and nutritional support, may also be necessary.

Parasitic infections

Treatment for internal and external parasites typically involves anti-parasitic medications prescribed by a veterinarian. The specific medication and dosage will depend on the type of parasite and the severity of the infection.

Respiratory infections

Antibiotics or antifungal medications may be prescribed to treat bacterial or fungal respiratory infections, respectively. Supportive care, including proper husbandry adjustments, may also be needed to aid recovery.


For mild impactions, a veterinarian may recommend laxatives, warm baths, or gentle abdominal massages. In severe cases, surgery might be necessary to remove the blockage.

Shedding issues (dysecdysis)

For retained skin, increasing humidity and providing a moist hide can help. In some cases, gentle manual removal of the retained skin may be necessary, but consult your veterinarian before attempting this to avoid injury.


Fluid therapy, either orally or through injections, may be administered by a veterinarian to rehydrate the gecko. Proper husbandry adjustments, such as ensuring access to clean water and maintaining appropriate humidity levels, are crucial for preventing dehydration.

It is essential to address any health concerns promptly and follow your veterinarian’s recommendations for treatment and care. Proper husbandry, regular check-ups, and a balanced diet can help prevent many common diseases in leopard geckos and contribute to their overall well-being.

Importance of regular veterinary check-ups

Regular veterinary check-ups play a crucial role in maintaining the health and well-being of your leopard gecko. These visits allow early detection and intervention for potential health issues, ensuring your pet receives timely and appropriate care. The importance of regular veterinary check-ups for leopard geckos can be expounded on through the following points:

  • Preventative care: Routine veterinary visits allow for proactive assessment and care, including parasite screening, physical examinations, and consultations on husbandry practices. This helps prevent the development or escalation of various health issues.
  • Early detection: Regular check-ups increase the likelihood of identifying potential health concerns before they become severe, allowing for more effective treatment and better outcomes.
  • Nutritional assessment: A veterinarian can evaluate your leopard gecko’s diet and recommend adjustments, ensuring your pet receives adequate nutrition to support its growth and overall health.
  • Monitoring growth and development: Regular visits help track your gecko’s growth, weight, and overall development, allowing your veterinarian to identify any concerns or abnormalities that may require attention.
  • Vaccinations and deworming (when applicable): Although leopard geckos typically do not require vaccinations, some reptiles may need deworming or other preventive treatments. Your veterinarian can advise you on the appropriate course of action for your pet.
  • Tailored advice: A reptile veterinarian can provide tailored recommendations on your leopard gecko’s specific needs, such as proper husbandry, diet, and environmental enrichment. This ensures your pet receives the best care possible.
  • Establishing a veterinary relationship: Regular check-ups help build a relationship between you, your leopard gecko, and your veterinarian. This familiarity can be beneficial in case of emergencies, as your veterinarian will already have an understanding of your gecko’s medical history and baseline health.
  • Education: Veterinary visits are an opportunity to learn more about your leopard gecko’s health, behavior, and care. Your veterinarian can answer questions and provide guidance on how to best care for your pet.

In summary, regular veterinary check-ups are essential for maintaining your leopard gecko’s health, ensuring early detection of potential issues, and providing tailored care and advice. By investing in routine veterinary visits, you can significantly contribute to your pet’s overall well-being and longevity.


In conclusion, leopard geckos, like any other pets, can carry diseases that may affect their health and well-being. However, the risk of transmission to humans or other pets is generally low. By practicing proper husbandry, providing a balanced diet, and scheduling regular veterinary check-ups, you can minimize the risk of diseases and ensure a healthy and thriving environment for your leopard gecko. 

It is essential to be vigilant for signs of illness and seek prompt veterinary care when necessary. Ultimately, understanding the potential health risks and taking appropriate preventive measures will lead to a rewarding and enjoyable experience for both you and your pet.

Read More:

How To Tell If Your Leopard Gecko Is Blind? 5 Signs To Be Aware Of!

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